ea0070aep743 | Pituitary and Neuroendocrinology | ECE2020
Felder Susan
, Zechmann Stefan
, Baur Katharina
, Seelig Eleonora
, Christ Emanuel
, Holbro Andreas
, Potlukova Eliska
Introduction: Central hypothyroidism is rare, estimated to occur in 1:20,000 to 1:80,000 in the general population. Pituitary mass lesions and adverse effects of their treatment are the most common causes of central hypothyroidism. In recent years, the incidence of pituitary hormonal deficiencies as adverse effects of novel molecular targeting anticancer drugs has risen sharply. Especially checkpoint inhibitors are associated with partial or complete hypopituitarism. In this r...